bsm-61194R-Biotin

DATASHEET

Host: Rabbit

Target Protein: Histone H2A

Modification Site: Ser129

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 852283

Swiss Prot: P04912

Source: KLH conjugated synthetic peptide derived from yeast Histone H2A around the phosphorylation site of S129

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Core component of nucleosome which plays a central role in DNA double strand break (DSB) repair. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:500-2000)

Predicted Molecular Weight: 14

Cross Reactive Species: Human
Yeast

For research use only. Not intended for diagnostic or therapeutic use.