bsm-61264R-Biotin

DATASHEET

Host: Rabbit

Target Protein: IRAKM

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 11213

Swiss Prot: Q9Y616

Source: KLH conjugated synthetic peptide derived from human IRAK3

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Putative inactive protein kinase which regulates signaling downstream of immune receptors including IL1R and Toll-like receptors.Inhibits dissociation of IRAK1 and IRAK4 from the Toll-like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex.Upon IL33-induced lung inflammation, positively regulates expression of IL6, CSF3, CXCL2 and CCL5 mRNAs in dendritic cells.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)
IP(1-2ug)

Predicted Molecular Weight: 68

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.