bsm-61302R [Primary Antibody]
FANCD2 Recombinant Antibody
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Host: Rabbit

Target Protein: FANCD2

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 2177

Swiss Prot: Q9BXW9

Source: KLH conjugated synthetic peptide derived from human FANCD2

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Required for maintenance of chromosomal stability. Promotes accurate and efficient pairing of homologs during meiosis. Involved in the repair of DNA double-strand breaks, both by homologous recombination and single-strand annealing. May participate in S phase and G2 phase checkpoint activation upon DNA damage. Plays a role in preventing breakage and loss of missegregating chromatin at the end of cell division, particularly after replication stress.

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))
IF(ICC)(IF(ICC)(1:50-200))
IP(IP(1:20-50))

Predicted Molecular Weight: 164


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with FANCD2 monoclonal antibody, unconjugated (bsm-61302R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.