bsm-61315R-BF488

DATASHEET

Host: Rabbit

Target Protein: Argonaute 3/eIF2C3

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 192669

Swiss Prot: Q9H9G7

Source: KLH conjugated synthetic peptide derived from human eIF2C3

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Proposed to be involved in stabilization of small RNA derivates (siRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent siRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.

Conjugation: AbBy Fluor-488

Excitation/ Emission: 499nm/519nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)

Predicted Molecular Weight: 97

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.