bsm-61337R [Primary Antibody]
NOTCH4 Recombinant Antibody
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Host: Rabbit

Target Protein: NOTCH4

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 4855

Swiss Prot: Q99466

Source: KLH conjugated synthetic peptide derived from human Notch 4

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Functions as a receptor for membrane-bound ligands Jagged1, Jagged2 and Delta1 to regulate cell-fate determination. Upon ligand activation through the released notch intracellular domain (NICD) it forms a transcriptional activator complex with RBPJ/RBPSUH and activates genes of the enhancer of split locus. Affects the implementation of differentiation, proliferation and apoptotic programs. May regulate branching morphogenesis in the developing vascular system.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 210


Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Western blot analysis of Mouse lung lysate. Using NOTCH4 (bsm-61337R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.