bsm-61349R-BF647

DATASHEET

Host: Rabbit

Target Protein: CDC42

Modification Site: Ser71

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 998

Swiss Prot: P60953,P63000

Source: KLH conjugated synthetic peptide derived from human Cdc42 around the phosphorylation site of S71

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Rac and Cdc42 are members of the Rho-GTPase family. In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac1 and Cdc42, the most widely studied of this group, are ubiquitously expressed. Rac2 is expressed in cells of hematopoietic origin, and Rac3, while highly expressed in brain, is also found in many other tissues. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development.

Conjugation: AbBy Fluor-647

Excitation/ Emission: 650nm/665nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:300-5000)

Predicted Molecular Weight: 21

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.