bsm-61354R

DATASHEET

Host: Rabbit

Target Protein: CBL (Tyr774)

Modification Site: Tyr774

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 867

Swiss Prot: P22681

Source: KLH conjugated synthetic peptide derived from human CBL around the phosphorylation site of Y774

Purification: Purified Polyclonal A

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome.

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:300-5000)
IHC-P(1:200-400)
IHC-F(1:100-500)
IF
Flow-Cyt(1ug/Test)

Predicted Molecular Weight: 100

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.