bsm-61355R-BF405

DATASHEET

Host: Rabbit

Target Protein: CBL (Ser669)

Modification Site: Ser669

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 867

Swiss Prot: P22681

Source: KLH conjugated synthetic peptide derived from human CBL around the phosphorylation site of S669

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome.

Conjugation: AbBy Fluor-405

Excitation/ Emission: 401nm/421nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))

Predicted Molecular Weight: 100

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.