bsm-61416R [Primary Antibody]
TRF1 Recombinant Antibody
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Host: Rabbit

Target Protein: TRF1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 7013

Swiss Prot: P54274

Source: KLH conjugated synthetic peptide derived from human TERF1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Plays an influential role in cellular immortalization and cellular senescence. TRF1 negatively regulates telomere elongation, while TRF2 protects the chromosome ends by inhibiting end-to-end fusions. Down-regulation of TRF expression in tumor cells may contribute to cell immortalization and malignant progression.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 50


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with TERF1 monoclonal antibody, unconjugated (bsm-61416R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.