bsm-61443R-APC

DATASHEET

Host: Rabbit

Target Protein: Noxa

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5366

Swiss Prot: Q13794

Source: KLH conjugated synthetic peptide derived from human PMAIP1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Noxa is a pro-apoptotic Bcl-2 family protein that contains a single Bcl-2 homology (BH3) domain. Promotes activation of caspases and apoptosis. Promotes mitochondrial membrane changes and efflux of apoptogenic proteins from the mitochondria. Contributes to p53/TP53-dependent apoptosis after radiation exposure. Promotes proteasomal degradation of MCL1.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)

Predicted Molecular Weight: 6

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.