bsm-61445R-FITC

DATASHEET

Host: Rabbit

Target Protein: Integrin beta 4/CD104

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 3691

Swiss Prot: P16144

Source: KLH conjugated synthetic peptide derived from human Integrin beta 4

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Integrin alpha-6/beta-4 is a receptor for laminin. Plays a critical structural role in the hemidesmosome of epithelial cells. Is required for the regulation of keratinocyte polarity and motility. ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))
IF(IHC-P)(IF(IHC-P)(1:50-200))

Predicted Molecular Weight: 202

Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.