bsm-61458R [Primary Antibody]
RAC1/2/3 Recombinant Antibody
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Host: Rabbit

Target Protein: RAC1/2/3

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5879

Swiss Prot: P63000,P15153,P60763

Source: KLH conjugated synthetic peptide derived from human Rac1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

In mammals, Rac exists as three isoforms, Rac1, Rac2 and Rac3, which are highly similar in sequence. Rac and Cdc42 play key signaling roles in cytoskeletal reorganization, membrane trafficking, transcriptional regulation, cell growth and development. GTP binding stimulates the activity of Rac/Cdc42, and the hydrolysis of GTP to GDP through the protein's intrinsic GTPase activity, rendering it inactive.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 21


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with RAC1/2/3 monoclonal antibody, unconjugated (bsm-61458R) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.