bsm-61495R [Primary Antibody]
PCSK9 Recombinant Antibody
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Host: Rabbit

Target Protein: PCSK9

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 255738

Swiss Prot: Q8NBP7

Source: KLH conjugated synthetic peptide derived from human PCSK9

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Crucial player in the regulation of plasma cholesterol homeostasis. Binds to low-density lipid receptor family members: low density lipoprotein receptor (LDLR), very low density lipoprotein receptor (VLDLR), apolipoprotein E receptor (LRP1/APOER) and apolipoprotein receptor 2 (LRP8/APOER2), and promotes their degradation in intracellular acidic compartments.

Size: 100ul

Concentration: Lot dependent

Predicted Molecular Weight: 74


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with PCSK9 monoclonal antibody, unconjugated (bsm-61495R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.