bsm-61526R [Primary Antibody]
FRS2 Recombinant Antibody
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Host: Rabbit

Target Protein: FRS2

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 10818

Swiss Prot: Q8WU20

Source: KLH conjugated synthetic peptide derived from human FGFR substrate 2

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 57


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with FRS2 monoclonal antibody, unconjugated (bsm-61526R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.