bsm-61560R [Primary Antibody]
CD209/DC-SIGN Recombinant Antibody
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Host: Rabbit

Target Protein: CD209/DC-SIGN

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 30835

Swiss Prot: Q9NNX6

Source: KLH conjugated synthetic peptide derived from human CD209

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Pathogen-recognition receptor expressed on the surface of immature dendritic cells (DCs) and involved in initiation of primary immune response. Thought to mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. The receptor returns to the cell membrane surface and the pathogen-derived antigens are presented to resting T-cells via MHC class II proteins to initiate the adaptive immune response.

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:300-5000)

Predicted Molecular Weight: 46


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Western blot analysis of HACAT cell lysate. Using CD209/DC-SIGN (bsm-61560R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.