bsm-61566R-BF488

DATASHEET

Host: Rabbit

Target Protein: CYP3A4

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 1576

Swiss Prot: P08684

Source: KLH conjugated synthetic peptide derived from human Cytochrome P450 3A4

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

A cytochrome P450 monooxygenase involved in the metabolism of sterols, steroid hormones, retinoids and fatty acids. Mechanistically, uses molecular oxygen inserting one oxygen atom into a substrate, and reducing the second into a water molecule, with two electrons provided by NADPH via cytochrome P450 reductase (NADPH--hemoprotein reductase). Catalyzes the hydroxylation of carbon-hydrogen bonds.

Conjugation: AbBy Fluor-488

Excitation/ Emission: 499nm/519nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))
IF(IHC-P)(IF(IHC-P)(1:100-500))

Predicted Molecular Weight: 57

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.