bsm-61576R-FITC

DATASHEET

Host: Rabbit

Target Protein: RASSF1A

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 11186

Swiss Prot: Q9NS23

Source: KLH conjugated synthetic peptide derived from human RASSF1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Potential tumor suppressor. Required for death receptor-dependent apoptosis. Mediates activation of STK3/MST2 and STK4/MST1 during Fas-induced apoptosis by preventing their dephosphorylation. When associated with MOAP1, promotes BAX conformational change and translocation to mitochondrial membranes in response to TNF and TNFSF10 stimulation. Isoform A interacts with CDC20, an activator of the anaphase-promoting complex, APC, resulting in the inhibition of APC activity and mitotic progression.

Conjugation: FITC

Excitation/ Emission: 494nm/518nm

Size: 100µL

Concentration: Lot dependent

Applications: IF(IHC-P)(IF(IHC-P)(1:50-200))

Predicted Molecular Weight: 39

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.