bsm-61593R [Primary Antibody]
PRKD1/PKC mu Recombinant Antibody
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Host: Rabbit

Target Protein: PRKD1/PKC mu

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5587

Swiss Prot: Q15139

Source: KLH conjugated synthetic peptide derived from human PKC mu

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Serine/threonine-protein kinase that converts transient diacylglycerol (DAG) signals into prolonged physiological effects downstream of PKC, and is involved in the regulation of MAPK8/JNK1 and Ras signaling, Golgi membrane integrity and trafficking, cell survival through NF-kappa-B activation, cell migration, cell differentiation by mediating HDAC7 nuclear export, cell proliferation via MAPK1/3 (ERK1/2) signaling, and plays a role in cardiac hypertrophy, VEGFA-induced angiogenesis, genotoxic-induced apoptosis and flagellin-stimulated inflammatory response

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 102


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with PRKD1/PKC mu monoclonal antibody, unconjugated (bsm-61593R) at 1:2000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.