bsm-61653R [Primary Antibody]
TRADD Recombinant Antibody
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Host: Rabbit

Target Protein: TRADD

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 8717

Swiss Prot: Q15628

Source: KLH conjugated synthetic peptide derived from human TRADD

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Adapter molecule for TNFRSF1A/TNFR1 that specifically associates with the cytoplasmic domain of activated TNFRSF1A/TNFR1 mediating its interaction with FADD.Overexpression of TRADD leads to two major TNF-induced responses, apoptosis and activation of NF-kappa-B.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 34


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with TRADD monoclonal antibody, unconjugated (bsm-61653R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.