bsm-61658R [Primary Antibody]
RNF8 Recombinant Antibody
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Host: Rabbit

Target Protein: RNF8

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 9025

Swiss Prot: O76064

Source: KLH conjugated synthetic peptide derived from human RNF8

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:300-5000)

Predicted Molecular Weight: 56


Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

Western blot analysis of human fetal kidney lysate. Using RNF8 (bsm-61658R) monoclonal antibody at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.