bsm-61658R-RBITC

DATASHEET

Host: Rabbit

Target Protein: RNF8

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 9025

Swiss Prot: O76064

Source: KLH conjugated synthetic peptide derived from human RNF8

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites.

Conjugation: RBITC

Excitation/ Emission: 570nm/595nm

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)

Predicted Molecular Weight: 56

Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.