bsm-61683R [Primary Antibody]
CBX7 Recombinant Antibody
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Host: Rabbit

Target Protein: CBX7

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 23492

Swiss Prot: O95931

Source: KLH conjugated synthetic peptide derived from human CBX7

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 28


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with CBX7 monoclonal antibody, unconjugated (bsm-61683R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.