bsm-61694R [Primary Antibody]
KSR1 Recombinant Antibody
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Host: Rabbit

Target Protein: KSR1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 8844

Swiss Prot: Q8IVT5

Source: KLH conjugated synthetic peptide derived from human KSR1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Part of a multiprotein signaling complex which promotes phosphorylation of Raf family members and activation of downstream MAP kinases.Independently of its kinase activity, acts as MAP2K1/MEK1 and MAP2K2/MEK2-dependent allosteric activator of BRAF; upon binding to MAP2K1/MEK1 or MAP2K2/MEK2, dimerizes with BRAF and promotes BRAF-mediated phosphorylation of MAP2K1/MEK1 and/or MAP2K2/MEK2.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 102


Cross Reactive Species: Human
Mouse

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with KSR1 monoclonal antibody, unconjugated (bsm-61694R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.