bsm-61708R-RBITC

DATASHEET

Host: Rabbit

Target Protein: MELK

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 9833

Swiss Prot: Q14680

Source: KLH conjugated synthetic peptide derived from human MELK

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Serine/threonine-protein kinase involved in various processes such as cell cycle regulation, self-renewal of stem cells, apoptosis and splicing regulation. Has a broad substrate specificity; phosphorylates BCL2L14, CDC25B, MAP3K5/ASK1 and ZNF622. Acts as an activator of apoptosis by phosphorylating and activating MAP3K5/ASK1. Acts as a regulator of cell cycle, notably by mediating phosphorylation of CDC25B, promoting localization of CDC25B to the centrosome and the spindle poles during mitosis.

Conjugation: RBITC

Excitation/ Emission: 570nm/595nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))

Predicted Molecular Weight: 75

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.