bsm-61755R [Primary Antibody]
PHOX2B Recombinant Antibody
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Host: Rabbit

Target Protein: PHOX2B

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 8929

Swiss Prot: Q99453

Source: KLH conjugated synthetic peptide derived from human PHOX2B

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 32


Cross Reactive Species: Human

Predicted Cross Reactive Species: Mouse

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with PHOX2B monoclonal antibody, unconjugated (bsm-61755R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.