bsm-61831R-APC

DATASHEET

Host: Rabbit

Target Protein: IL-23

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 51561

Swiss Prot: Q9NPF7

Source: KLH conjugated synthetic peptide derived from human IL 23A

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Associates with IL12B to form the pro-inflammatory cytokine IL-23 that plays different roles in innate and adaptive immunity.Released by antigen-presenting cells such as dendritic cells or macrophages, binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R to activate JAK2 and TYK2 which then phosphorylate the receptor to form a docking site leading to the phosphorylation of STAT3 and STAT4.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))

Predicted Molecular Weight: 21

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.