bsm-61845R [Primary Antibody]
MMP17 Recombinant Antibody
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Host: Rabbit

Target Protein: MMP17

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 4326

Swiss Prot: Q9ULZ9

Source: KLH conjugated synthetic peptide derived from human MMP17

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Endopeptidase that degrades various components of the extracellular matrix, such as fibrin. May be involved in the activation of membrane-bound precursors of growth factors or inflammatory mediators, such as tumor necrosis factor-alpha. May also be involved in tumoral process. Cleaves pro-TNF-alpha at the '74-Ala-|-Gln-75' site. Not obvious if able to proteolytically activate progelatinase A. Does not hydrolyze collagen types I, II, III, IV and V, gelatin, fibronectin, laminin, decorin nor alpha1-antitrypsin.

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:300-5000)
IHC-P(1ug/Test)
IHC-F(1:100-500)
IF
ICC/IF(1:50-100)

Predicted Molecular Weight: 67


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with MMP17 monoclonal antibody, unconjugated (bsm-61845R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.