bsm-61954R

DATASHEET

Host: Rabbit

Target Protein: CD112

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5819

Swiss Prot: Q92692

Source: KLH conjugated synthetic peptide derived from human Nectin 2

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Modulator of T-cell signaling. Can be either a costimulator of T-cell function, or a coinhibitor, depending on the receptor it binds to. Upon binding to CD226, stimulates T-cell proliferation and cytokine production, including that of IL2, IL5, IL10, IL13, and IFNG. Upon interaction with PVRIG, inhibits T-cell proliferation. These interactions are competitive.

Size: 100ul

Concentration: Lot dependent

Predicted Molecular Weight: 58

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.