bsm-62028R-Biotin

DATASHEET

Host: Rabbit

Target Protein: Niemann Pick C1 Like 1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 29881

Swiss Prot: Q9UHC9

Source: KLH conjugated synthetic peptide derived from human NPC1L1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C for 12 months.

Background:

Plays a major role in cholesterol homeostasis.Critical for the uptake of cholesterol across the plasma membrane of the intestinal enterocyte.Involved in plant sterol absorption, it transports sitosterol, although at lower rates than cholesterol.Is the direct molecular target of ezetimibe, a drug that inhibits cholesterol absorption and is approved for the treatment of hypercholesterolemia.

Conjugation: Biotin

Excitation/ Emission: N/A

Size: 100ul

Concentration: Lot dependent

Applications: WB(1:300-5000)

Predicted Molecular Weight: 149

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.