bsm-62046R [Primary Antibody]
TC10 Recombinant Antibody
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Host: Rabbit

Target Protein: TC10

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 23433

Swiss Prot: P17081

Source: KLH conjugated synthetic peptide derived from human TC10

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. May play a role in CFTR trafficking to the plasma membrane. Causes the formation of thin, actin-rich surface projections called filopodia.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 23


Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with TC10 monoclonal antibody, unconjugated (bsm-62046R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.