bsm-62062R [Primary Antibody]
Cripto Recombinant Antibody
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Host: Rabbit

Target Protein: Cripto

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 6997

Swiss Prot: P13385

Source: KLH conjugated synthetic peptide derived from human Cripto

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

GPI-anchored cell membrane protein involved in Nodal signaling. Cell-associated CRIPTO acts as a Nodal coreceptor in cis. Shedding of CRIPTO by TMEM8A modulates Nodal signaling by allowing soluble CRIPTO to act as a Nodal coreceptor on other cells. Could play a role in the determination of the epiblastic cells that subsequently give rise to the mesoderm.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 21


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with Cripto monoclonal antibody, unconjugated (bsm-62062R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.