bsm-62077R-BF488

DATASHEET

Host: Rabbit

Target Protein: SorLA

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 6653

Swiss Prot: Q92673

Source: KLH conjugated synthetic peptide derived from human Sortilin related receptor

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Sorting receptor that directs several proteins to their correct location within the cell (Probable). Along with AP-1 complex, involved Golgi apparatus - endosome sorting.Sorting receptor for APP, regulating its intracellular trafficking and processing into amyloidogenic-beta peptides. Retains APP in the trans-Golgi network, hence preventing its transit through late endosomes where amyloid beta peptides Abeta40 and Abeta42 are generated.

Conjugation: AbBy Fluor-488

Excitation/ Emission: 499nm/519nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:500-2000)
IHC-P(1:20-50)
IHC-F(1:100-500)
IF

Predicted Molecular Weight: 248

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.