bsm-62207R [Primary Antibody]
TIRAP Recombinant Antibody
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Host: Rabbit

Target Protein: TIRAP

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 114609

Swiss Prot: P58753

Source: KLH conjugated synthetic peptide derived from human TIRAP

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Adapter involved in TLR2, TLR4 and RAGE signaling pathways in the innate immune response. Acts via IRAK2 and TRAF-6, leading to the activation of NF-kappa-B, MAPK1, MAPK3 and JNK, and resulting in cytokine secretion and the inflammatory response. Positively regulates the production of TNF-alpha (TNF) and interleukin-6 (IL6).

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 24


Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with TIRAP monoclonal antibody, unconjugated (bsm-62207R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.