bsm-62288R-BF594

DATASHEET

Host: Rabbit

Target Protein: ARTS1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 51752

Swiss Prot: Q9NZ08

Source: KLH conjugated synthetic peptide derived from human ERAP1

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecules. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus.

Conjugation: AbBy Fluor-594

Excitation/ Emission: 590nm/617nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:500-2000)
IF()

Predicted Molecular Weight: 107

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.