DATASHEET
Host:
Rabbit
Target Protein:
ACVR2A
Clonality:
Recombinant
Isotype:
IgG
Entrez Gene:
92
Swiss Prot:
P27037
Source:
KLH conjugated synthetic peptide derived from human ACVR2A
Purification:
Purified by Protein A.
Storage Buffer:
0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol
Storage:
Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
Background:
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for activin A, activin B and inhibin A.
VALIDATION IMAGES
25 ug total protein per lane of various lysates (see on figure) probed with ACVR2A monoclonal antibody, unconjugated (bsm-62312R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.
25 ug total protein per lane of various lysates (see on figure) probed with ACVR2A monoclonal antibody, unconjugated (bsm-62312R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.