bsm-62326R [Primary Antibody]
DOCK2 Recombinant Antibody
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Host: Rabbit

Target Protein: DOCK2

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 1794

Swiss Prot: Q92608

Source: KLH conjugated synthetic peptide derived from human Dedicator of cytokinesis protein 2

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.

Size: 100µL

Concentration: Lot dependent

Applications: WB(WB(1:500-2000))
IHC-P(IHC-P(1:100-200))
IHC-F(IHC-F(1:100-200))
IF(IHC-P)(IF(IHC-P)(1:100-200))

Predicted Molecular Weight: 212


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with DOCK2 monoclonal antibody, unconjugated (bsm-62326R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.