bsm-62533R [Primary Antibody]
SCIN Recombinant Antibody
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Host: Rabbit

Target Protein: SCIN

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 85477

Swiss Prot: Q9Y6U3

Source: KLH conjugated synthetic peptide derived from human Scinderin

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Ca2+-dependent actin filament-severing protein that has a regulatory function in exocytosis by affecting the organization of the microfilament network underneath the plasma membrane.Severing activity is inhibited by phosphatidylinositol 4,5-bis-phosphate.In vitro, also has barbed end capping and nucleating activities in the presence of Ca2+. Required for megakaryocyte differentiation, maturation, polyploidization and apoptosis with the release of platelet-like particles.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 80


Cross Reactive Species: Mouse
Rat

Predicted Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with SCIN monoclonal antibody, unconjugated (bsm-62533R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.