bsm-62608R-APC

DATASHEET

Host: Rabbit

Target Protein: BLNK

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 29760

Swiss Prot: Q8WV28

Source: KLH conjugated synthetic peptide derived from human BLNK

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Functions as a central linker protein, downstream of the B-cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B-cell function and development. Plays a role in the activation of ERK/EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF-kappa-B and NFAT. Plays an important role in BCR-mediated PLCG1 and PLCG2 activation and Ca2+ mobilization and is required for trafficking of the BCR to late endosomes.

Conjugation: APC

Excitation/ Emission: 650nm/660nm

Size: 100µL

Concentration: Lot dependent

Applications: FCM(FCM(1:50-100))
IF(IHC-P)(IF(IHC-P)(1:50-200))
IF(ICC)(IF(ICC)(1:100-500))

Predicted Molecular Weight: 50

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.