bsm-62623R-BF594

DATASHEET

Host: Rabbit

Target Protein: UBA3

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 9039

Swiss Prot: Q8TBC4

Source: KLH conjugated synthetic peptide derived from human UBA3

Purification: Purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Catalytic subunit of the dimeric UBA3-NAE1 E1 enzyme. E1 activates NEDD8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a NEDD8-UBA3 thioester and free AMP. E1 finally transfers NEDD8 to the catalytic cysteine of UBE2M. Down-regulates steroid receptor activity. Necessary for cell cycle progression.

Conjugation: AbBy Fluor-594

Excitation/ Emission: 590nm/617nm

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:500-2000)

Predicted Molecular Weight: 52

Cross Reactive Species: Human
Mouse
Rat

For research use only. Not intended for diagnostic or therapeutic use.