bsm-62710R [Primary Antibody]
GLCNE Recombinant Antibody
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Host: Rabbit

Target Protein: GLCNE

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 10020

Swiss Prot: Q9Y223

Source: KLH conjugated synthetic peptide derived from human GNE

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Bifunctional enzyme that possesses both UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine kinase activities, and serves as the initiator of the biosynthetic pathway leading to the production of N-acetylneuraminic acid (NeuAc), a critical precursor in the synthesis of sialic acids. By catalyzing this pivotal and rate-limiting step in sialic acid biosynthesis, this enzyme assumes a pivotal role in governing the regulation of cell surface sialylation.

Size: 100µL

Concentration: Lot dependent

Predicted Molecular Weight: 79


Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.

VALIDATION IMAGES

25 ug total protein per lane of various lysates (see on figure) probed with GLCNE monoclonal antibody, unconjugated (bsm-62710R) at 1:1000 dilution and 4°C overnight incubation. Followed by conjugated secondary antibody incubation at r.t. for 60 min.