bsm-62786R

DATASHEET

Host: Rabbit

Target Protein: HTRA1

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 5654

Swiss Prot: Q92743

Source: KLH conjugated synthetic peptide derived from human Serine protease HTRA1

Purification: Purified by Protein A.

Storage Buffer: 0.01M TBS (pH 7.4), 1% BSA, 0.02% Proclin 300, and 50% Glycerol

Storage: Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.

Background:

Serine protease with a variety of targets, including extracellular matrix proteins such as fibronectin. HTRA1-generated fibronectin fragments further induce synovial cells to up-regulate MMP1 and MMP3 production. May also degrade proteoglycans, such as aggrecan, decorin and fibromodulin. Through cleavage of proteoglycans, may release soluble FGF-glycosaminoglycan complexes that promote the range and intensity of FGF signals in the extracellular space.

Size: 100µL

Concentration: Lot dependent

Applications: WB(1:300-5000)
ICC/IF(1:50-100)

Predicted Molecular Weight: 51

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.