bsm-63061R-RBITC

DATASHEET

Host: Rabbit

Target Protein: NPHS2

Clonality: Recombinant

Isotype: IgG

Entrez Gene: 7827

Swiss Prot: Q9NP85

Source: A synthesized peptide derived from human Podocin

Purification: purified by Protein A.

Storage Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Background:

Podocin is an important member of a group of proteins shown to be associated with the slit diaphragm. Podocin belongs to the band 7 stomatin family of lipid raft-associated proteins. It is a hairpin like integral membrane protein with intracellular N and C termini. Podocin is located at the insertion site of the slit membrane, and is thought to act as a scaffold protein required to maintain or regulate the structural integrity of the slit diaphragm. It plays a role in the regulation of glomerular permeability, acting probably as a linker between the plasma membrane and the cytoskeleton.

Conjugation: RBITC

Excitation/ Emission: 570nm/595nm

Size: 100ul

Concentration: 1mg/ml

Applications: IHC-F(1:100-500)
IF(1:100-500)
IHC-P(1:100-500)

Predicted Molecular Weight: 42 kDa

Cross Reactive Species: Human
Rat

For research use only. Not intended for diagnostic or therapeutic use.