bsm-70091M

DATASHEET

Host: Mouse

Target Protein: FOX1

Specificity: Specific for endogenous levels of the ~46/48 kD FOX1 protein doublet.

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 54715

Swiss Prot: Q9NWB1

Source: Recombinant protein taken from the N-terminus of human FOX1 expressed in and purified from E. Coli.

Purification: Purified by Protein G.

Storage Buffer: PBS + 10 mM NaN3.

Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cy

Background:

FOX1, also known as ataxin-2 binding protein 1 (A2BP1), is a neuron specific RNA-binding protein that has been shown to regulate a wide range of alternative splicing events implicated in neuronal development and maturation including transcription factors and synaptic proteins (Fogel et al., 2012). Defects in FOX1 have also been associated with autism (Martin et al., 2007), attention-deficit hyperactivity disorder (Elia et al., 2010) and schizophrenia (Xu et al., 2008).

Size: 100µL

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IHC

Predicted Molecular Weight: 46/48

Cross Reactive Species: Human
Mouse
Rat
Bovine

For research use only. Not intended for diagnostic or therapeutic use.