bsm-70139M

DATASHEET

Host: Mouse

Target Protein: LAMP1

Specificity: Specific for endogenous levels of the ~100 kDa LAMP1 protein.

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 3916

Swiss Prot: P11279

Source: Recombinant full length human LAMP1 expressed in and purified from E. coli.

Purification: Purified by Protein G.

Storage Buffer: PBS + 10 mM NaN3.

Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cy

Background:

Lysosomal Associated Membrane Protein1 (LAMP1) is a protein that is localized primarily in lysosomes but may also be present on late endosomes and the plasma membrane. LAMP1 antibodies are therefore widely used as lysosome markers. It has recently been suggested that lysosomes are activated in microglia in the progression of multiple system atrophy (MSA) and thus play a key role in its pathology (Makioka et al., 2012).

Size: 100µL

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IHC

Predicted Molecular Weight: 100

Cross Reactive Species: Human

For research use only. Not intended for diagnostic or therapeutic use.