bsm-70215M

DATASHEET

Host: Mouse

Target Protein: Park7 (DJ-1)

Specificity: Specific for endogenous levels of the ~21 kDa Park7 protein.

Clonality: Monoclonal

Isotype: IgG1

Entrez Gene: 117287

Swiss Prot: O88767

Source: Full length recombinant human Park7 expressed in and purified from E. coli.

Purification: Purified by Protein G culture supernatant

Storage Buffer: PBS + 10 mM NaN3.

Storage: Recommended that the undiluted antibody be aliquoted into smaller working volumes (10-30 uL/vial depending on usage) upon arrival and stored long term at -20° C or -80° C, while keeping a working aliquot stored at 4° C for short term. Avoid freeze/thaw cy

Background:

Park7, also known as DJ-1, is a member of the peptidase C56 family of proteins and is thought to function as a molecular chaperone. Mutations in park7 have been associated with autosomal recessive, early onset Parkinson’s disease (Bonifati et al., 2003). Recently, park7 has been shown to inhibit microtubule associated protein 1B aggregation thus leading to neuronal apoptosis (Wang et al., 2011).

Size: 100µL

Concentration: Lot Dependent

Applications: WB(1:300-5000)
IHC

Predicted Molecular Weight: 21

Cross Reactive Species: Human
Mouse
Rat
Bovine

For research use only. Not intended for diagnostic or therapeutic use.